Autoimmune diseases a guide to clinical differential diagnosis of oral mucosal lesions continuing education course. A clinical condition characterized in the oral cavity by sharp lesions that look like they were cut out by a knife. Common problems of oral cavity linkedin slideshare. Oral health should not be taken for granted as it is an essential part of our everyday lives. Autoimmune diseases and their manifestations on oral.
Pdf autoimmune diseases and their manifestations on oral. Several systemic factors are known to contribute to oral diseases or conditions and among those are the intake of drugs. A number of skin diseases have oral manifestations, such as pemphigus, erythema multiforme, sle, lichen planus, psoriasis, viral infections, etc. Appearances vary greatly, but a typical malignant ulcer would be a persistent, expanding lesion which is totally. These include recurrent aphthous stomatitis ras, erythema multiforme em, the bullous diseases pemphigus vulgaris pv and mucous membrane pemphigoid mmp and lichen planus lp. Immunemediated diseases along with lesions in oral cavity. This category reflects the organization of international statistical classification of diseases and. Wikimedia commons has media related to diseases and disorders of oral cavity, salivary glands and jaws the main article for this category is oral and maxillofacial pathology.
The oral cavity can provide valuable clues to cutaneous disorders, and should be included in every skin examination. Many oromucosal diseases may arise as a direct expression of emotions or indirect result of psychological. Factor responsible for differences in immunity are age, nutrition and genetic factors. Autoimmune diseases may also be reflected in changes in the oral cavity that represent the first sign of the disease, or they may occur simultaneously with or later in the course of the disease. Lack of saliva predisposes patients to develop tooth cavities. Cancer of the oral cavity cancers involve body tissues whose cells are dividing and growing faster than cells are dying. Oral infections, a mirror of our overall health condition. The oral cavity diseases of the digestive system body.
If the halitosis is because of disease of the oral cavity, alimentary tract, or respiratory system, the cure will depend on eradicating the primary cause. Oral manifestations of autoimmune blistering diseases generally can affect any area of the oral cavity, including the gingiva, palate, buccal, tongue, floor of the mouth, and pharynx. Infections of the oral cavity are most commonly odontogenic in origin and include dental caries, periapical infections, gingivitis, periodontal infections and abscesses, and deep fascial space infections. Any whitish lesion in the oral cavity is called leukoplakia. Autoimmune diseases are disorders caused by a reaction of an individuals immune system to the tissues or organs of the persons own body. Some organisms are almost always present in a normal oral cavity and constitute constantnormal microbial flora. Infectious, reactive, and neoplastic entities may arise in the microscopic differential diagnosis of oral autoimmune disease. Pdf disorders of the oral cavity in parkinsons disease and. Hiv aids leukaemia crohns disease diabetes mellitus down syndrome sarcoidosis chediak higashi syndrome.
Symptoms can usually be managed, but people who have oral lichen planus need regular monitoring because they may be at risk of developing mouth cancer in the. Hanaoka and kashihara evaluated the prevalence of periodontal disease by counting the numbers of caries and remaining teeth in consecutive 60 to 79yearold patients with pd compared with two other patient groups. Table 1 prevalence of oral cavity involvement in autoimmune and inflammatory diseases. Autoimmune diseases a guide to clinical differential diagnosis of. Diseases and disorders that affect the oral cavity. Most diseases of oral mucosa are either autoimmune in nature or are the results of immunologicallymediated events. The oral cavity and oropharynx help you breathe, talk, eat, chew, and swallow. Oral lichen planus cant be passed from one person to another. The entities represented within this group may vary significantly by severity, clinical presentation, microscopic. The oral cavity, tongue, teeth and gums speak volumes about our health.
Oral cavity alterations diagnosis in cerebral palsy subjects. An early event in the disease mechanism involves keratinocyte antigen expression or unmasking of an antigen that may be a selfpeptide or a heat shock protein. When halitosis results from poor oral sanitation, the treatment is obviousregular daily tooth brushing and the use of an antiseptic mouthwash. The oral cavity is separated from the nasal cavity posteriorly by midline fusion of the secondary palate and anteriorly by the approximation of the primary palate to these shelves. Other problems like genetic factors and ageing may also influence oral health. The oral cavity is the primary site of many viral illnesses as well as a site with specific manifestations of more systemic viral disease. Instead, erosions and superficial ulcers more likely are observed.
Also, several autoimmune diseases such as sjogrens syndrome and pemphigus vulgaris have oral manifestations. Describe the blood and nerve supply of mucosa and muscles of palate and tongue 3. The addition of an autoimmune disease is referred to as secondary sjogren syndrome, 24. Know the signs and symptoms of oral cavity and oropharyngeal cancers.
Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. May 18, 2014 autoimmune diseases failure of the immune system to tolerate self tissues. This category reflects the organization of international statistical classification of diseases and related health problems, 10th revision. Review article nutrition in oral health and disease. Most body parts can be affected by these diseases, and even though treatments exist to control symptoms, there are no cures. It is a condition in which structural or functional damage is caused by the immunologically competent cells or antibodies against normal components of body. An expert can take one look at our open mouth and get a good idea of our overall problems. Ppt diseases of oral cavity powerpoint presentation.
Korczyn, 1,3 nir giladi, 1,3 and tanya gurevich 1,3. Involvement of areas beyond the oral cavity also may be a factor in overall disease management. Recognizing these oral lesions often provides important. Autoimmune diseases of the oral cavity systemic lupus. Oral cavity human tooth digestive diseases free 30day. Oral manifestations of gi diseases gastrointestinal society. The result of excessive cell growth is an enlarged mass. It can also manifest with hugely swollen lymph node swelling in anterior triangle of neck called scrofula. However, there are number of other infections that can manifest in the oral cavity when other microbes are present.
The two onehalves of the lower jaw arise from mesenchyme derived from the first branchial arch. Most of the lesions are in the form of ulcers or white patches. The excessive consumption of fried, spicy food, alcohol, smoking and drugs may lead to oral problems. Common problems that affects oral cavity articles factory. Autoimmune diseases of oral cavity most diseases of oral mucosa are either autoimmune in nature or are the results of immunologicallymediated events. Autoimmunity autoimmunity is the failure of an organism to recognize its own constituent parts as self, which results in an immune response against its own cells and tissues. The mouth is often the indicator or harbinger of more wide. Oral manifestations of systemic disease hairy leukoplakia. Winner of the standing ovation award for best powerpoint templates from presentations magazine. Another study was conducted to evaluate the buffering capacity, flow, saliva ph and dental caries incidence in children. The xerostomia is responsible for creating different manifestations of ss at the level of oral cavity. Microbial diseases of the mouth and oral cavity microbiology.
Diseases and disorders caused by oral microorganisms are very common and economically important, in particular dental caries loss of tooth integrity caused by. Adverse drug reactions, oral reactions, oral manifestations, mucosal lesions, drug pharmacodyanamics, introduction. Nutrition in oral health and disease gouri bhatia 1, shruti gupta 2, ankita arora 3, sameer saxena 4, neha sikka 5 1 department of periodontology, eklavya dental colleg e, kotputli, jaipur, rajasthan,303108. Oral cavity and oropharyngeal cancer early detection. The oral cavity is the entrance to the alimentary tract and. The oral cavity is a unique anatomical structure, characterised by the juxtaposition of soft and hard tissues and which is continuously subject to challenge by the external environment and foreign material. The disorder occurs when the immune system mounts an attack against cells of the oral mucous membranes for unknown reasons. Autoimmune bullous diseases are rare but represent a potentially devastating group of mucocutaneous diseases characterized by the presence of tissuebound immunoreactants and circulating autoantibodies against various target antigens with disease specificity 1. Apoptosis, autoimmune, bcl2, fas, fas l, dentinogenesis, keratinocyte.
Autoimmune diseases affecting the oral cavity may demonstrate clinical, histologic, and in some cases similar immunopathologic patterns. Disorders of the oral cavity in parkinsons disease and. All organs, cns, blood vessels, nose and oral cavity. Mucocutaneous and granulomatous lesions of the oral cavity alert the clinician to investigate the gastrointestinal tract.
Due to failure of an organism to recognize its own constituent parts as self leading to an immune response against its own cells and tissues. A mucous membrane of stratified squamous epithelium lines and protects the inside of the mouth. Our new crystalgraphics chart and diagram slides for powerpoint is a collection of over impressively designed datadriven chart and editable diagram s guaranteed to impress any audience. Identify the effect of nerve paralysis on those muscles and their related function 4. Also, halitosis oral malodour is caused by sulphide producing oral bacteria. Bad breath, oral cancer, cavities and gum problems are some of the common oral problems that affect oral cavity. Oral cavity human tooth digestive diseases free 30. Introduction concept of immunity and autoimmunity human body has got capacity to resist almost all types of organisms or toxins that tend to damage the tissues and organs. Find out how oral cavity and oropharyngeal cancers are tested for, diagnosed, and staged. Mucous membrane pemphigoid involves primarily oral mucosa, but mucosa of the nose.
Immunology is defined as the study of the molecular cells, organs and system for the recognition and disposal of foreign materials. Immunerelated disorders of the oral cavity may occur as primary disease process, secondary to systemic disease or neoplasm, or as a reaction to medications and other agents. These conditions are characterised by lesions of the oral mucosa often associated with extraoral. The subsites of the oral cavity include the upper and lower lips, the oral tongue anterior 23, floor of mouth, retromolartrigone, upper and lower alveolar ridges and gingiva, buccal mucosa, and hard palate figure 1. Some of these diseases affect the oral cavity and have a negative effect on oral. Genetic considerations of diseases and disorders that affect the oral cavity part 2. Immunity in the oral cavity british society for immunology. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. The anatomy of the oral tract ranging from the lips to the pharynx. Ppt diseases of oral cavity powerpoint presentation free. Review article nutrition in oral health and disease gouri bhatia 1, shruti gupta 2, ankita arora 3.
Kusama k 2016 microorganisms and cancer of the oral cavity integr cancer ci erap, 2016 doi 10. The main signs of the syndrome are related to the oral cavity. Differentiate different parts of the oral cavity 2. Stages and outlook prognosis after a cancer diagnosis, staging provides important information about the extent of cancer in the body and anticipated response to treatment. Infectious diseases of the oral cavity flashcards quizlet. Minor salivary glands throughout the oral cavity and oropharynx make saliva that keeps your mouth and throat moist and helps you digest food. Autoimmune diseases and their manifestations on oral cavity ncbi. They account for less than one percent of cases of extra pulmonary tuberculosis, are usually. Since the introduction of effective chemotherapy, tuberculous lesions of the oral cavity have become so infrequent that it is virtually a forgotten disease entity and pose a diagnostic problem. Karpi nski pozna n university of medical sciences pozna n, poland pozna n, poland, 2017.
Dental considerations in autoimmune diseases presented by amjath k malabar dental college 2. Oral manifestations of autoimmune blistering diseases. Oral manifestations of gi diseases although mainly expressing in the gastrointestinal gi tract, a digestive disorder may produce symptoms outside of the digestive system, or in a portion of this system far away from the primary disease site. Herpetic gingivostomatitis as described in viral infections of the skin and eyes, infections by herpes simplex virus type 1 hsv1 frequently manifest as oral herpes, also called acute herpes labialis and characterized by cold. Pregnant females may transmit to fetus during this stage. Health and diseases of oral cavity edited by tomasz m.
Autoimmune oral mucosal diseases dental clinics of north america. Dec 22, 2017 hiv aids leukaemia crohns disease diabetes mellitus down syndrome sarcoidosis chediak higashi syndrome. Carious lesions are the result of mineral dissolution of tooth structure by acid metabolic end products from bacteria that are present in the oral cavity and are capable of fermenting sugars. Oral lichen planus symptoms and causes mayo clinic. Disorders of the lips angular cheilitis perleche inflammatory reactionerythema and. Several gi conditions can give rise to symptoms in the oral cavity, within tissues in or around. Autoimmune diseases and their manifestations on oral cavity. Oral cavity anatomical and physiological specificities. Autoimmune disease manifestations in the oral cavity. Chart and diagram slides for powerpoint beautifully designed chart and diagram s for powerpoint with visually stunning graphics and animation effects. Tumors and growths in the oral cavity and oropharynx. There is a 3 week incubation period followed by flu like symptoms and possible hemoptysis if lung infection has occurred.